03268nam a2200337Ia 450000500170000000800470001724501250006410000620018970000640025126000580031525000180037330000350039130000100042650000190043602000180045565000270047365000190050065000230051965000250054265000250056765000350059265000300062765000150065765000150067205000210068754600150070850521720072333600090289533700150290433800110291920260803094237.0251212s2020    xx            000 0 und d©©©1 aRodak's hematology : bclinical principles and applications /cElaine M. Keohane; Jeanine M. Walenga; Catherine N. Otto.  aRodak`s hematology : clinical principles and applications  aKeohane, Elaine M.; Walenga, Jeanine M.; Otto, Catherine N.  aSingapore :bElsevier (Singapore) Pte. Ltd.,c©2020.  aSixth edition  axv, 887 pages: bIllustrations  c28 cm  aIncludes index  a9789814920353  aBlood cells physiology  aBlood diseases  aHealth and fitness  aHealth and wellbeing  aHematologic diseases  aHematologic diseases diagnosis  aHematologic Tests methods  aHematology  aHemostasis  a616.15 K43r 2020  ain English  a Part I: Introduction to hematology An overview of clinical laboratory hematology Quality assurance in hematology and hemostasis testing Part II: Blood cell production, structure, and function Cellular structure and function Hematopoiesis Erythrocyte production and destruction Erythrocyte metabolism and membrane structure and function Hemoglobin metabolism Iron kinetics and laboratory assessment Leukocyte development, kinetics, and functions Platelet production, structure, and function Part III: Laboratory evaluation of blood cells Manual, semiautomated, and point-of-care testing and hematology Automated blood cell analysis Examination of the peripheral blood film and correlation with the complete blood count Bone marrow examination Body fluid analysis in the hematology laboratory Part IV: Erythrocyte disorders Anemias: red blood cell morphology and approach to diagnosis Disorders of iron kinetics and heme metabolism Anemias caused by defects of DNA metabolism Bone marrow failure Introduction to increased destruction of erythrocytes Intrinsic defects leading to increased erythrocyte destruction Extrinsic defects leading to increased erythrocyte destruction-nonimmune causes Extrinsic defects leading to increased erythrocyte destruction-immune causes Hemoglobinopathies (Structural defects in hemoglobin) Thalassemias Part V: Leukocyte disorders Non-malignant leukocyte disorders Intro to hematologic malignancies Flow cytometric analysis in hematologic disorders Molecular diagnostics in the clinical laboratory Cytogenetics Acute leukemias Myeloproliferative neoplasms Myelodysplastic syndromes Mature lymphoid neoplasms Part VI: Hemostasis and thrombosis Normal hemostasis and coagulation Hemorrhagic disorders and laboratory assessment Qualitative disorders of platelets and vasculature Thrombocytopenia and thrombocytosis Thrombotic disorders and laboratory assessment Antithrombotic therapies and their laboratory assessment Laboratory evaluation of hemostasis Hemostasis and coagulation instrumentation Part VII: Hematology and hemostasis in selected populations Hematology and hemostasis in the pediatric, geriatric, and pregnant populations  atext  aunmediated  avolume