A microscale approach to organic laboratory techniques /
Pavia, Donald L.
A microscale approach to organic laboratory techniques / Donald L. Pavia, Gary M. Lampman, George S. Kriz, [and] Randall G. Engel. - Sixth edition - Boston, MA : Cengage Learning, 2018. - xvii, 1034 pages: illustrations 28 cm. - Cengage Learning Laboratory Series for Organic Chemistry .
Includes index
Experiment 1.Introduction to Microscale Laboratory.Experiment 2.Solubility.Experiment 3.Crystallization.Experiment 4.Extraction.Experiment 5.A Separation and Purification Scheme.Experiment 6.Chromatography.Experiment 7.Infrared Spectroscopy and Boiling Point Determination.Experiment 8.Simple and Fractional Distillation.Essay: Aspirin.Experiment 9.Acetylsalicylic Acid.Essay: Analgesics.Experiment 10. Isolation of the Active Ingredient in an Analgesic Drug.Experiment 11, Acetaminophen.Essay: Identification of Drugs.Experiment 12. TLC Analysis of Analgesic Drugs.Essay: Caffeine.Experiment 13. Isolation of Caffeine from Tea or Coffee.Essay: Esters -- Flavors and Fragrances.Experiment 14. Isopentyl Acetate (Banana Oil).Essay: Terpenes and Phenylpropanoids.Experiment 15. Essential Oils: Extraction of Oil of Cloves by Steam Distillation.Essay: Stereochemical Theory of Odor.Experiment 16. Spearmint and Caraway Oil: (+)- and (-)-Carvones.Essay: The Chemistry of Vision.Experiment 17. Isolation of Chlorophyll and Carotenoid Pigments from Spinach.Essay: Ethanol and Fermentation Chemistry.Experiment 18. Ethanol from Sucrose.Essay Molecular Modeling and Molecular Mechanics.Experiment 19. An Introduction to Molecular Modeling.Essay: Computational Chemistry -- Ab Initio and Semiempirical Methods.Experiment 20. Computational Chemistry.Experiment 21. Reactivities of Some Alkyl Halides.Experiment 22. Nucleophilic Substitution Reactions: Competing Nucleophiles.Experiment 23. Synthesis of n-Butyl Bromide and t-Pentyl Chloride.Experiment 24. 4-Methylcyclohexene.Essay: Fats and Oils.Experiment 25. Methyl Stearate from Methyl Oleate.Essay: Soap.Experiment 26. Preparation of Soap.Essay: Petroleum and Fossil Fuels.Experiment 27. Gas Chromatographic Analysis of Gasolines.Essay: Biofuels.Experiment 28. Biodiesel.Essay: Green Chemistry.Experiment 29. Chiral Reduction of Ethyl Acetoacetate; Optical Purity Determination.Experiment 30. Nitration of Aromatic Compounds Using a Recyclable Catalyst.Experiment 31. Reduction of Ketones Using Carrots as Biological Reducing Agents.Experiment 32. Resolution of Phenylethylamine and Determination of Optical Purity.Experiment 33. An Oxidation-Reduction Scheme: Borneol, Camphor, Isoborneol.Experiment 34. Multi-Step Reaction Sequences: The Conversion of Benzaldehydeto Benzilic Acid.Experiment 35. Triphenylmethanol and Benzoic Acid.Experiment 36. Aqueous-based Organozinc Reactions.Experiment 37. Sonogashira Coupling of Iodosubstituted Aromatic Compounds with Alkynes Using a Palladium Catalyst.Experiment 38. Grubbs-Catalyzed Metathesis of Eugenol with 1,4-Butanediol to Prepare a Natural Product.Experiment 39. The Aldol Condensation Reaction: Preparation of Benzalacetophenones (Chalcones).Experiment 40. A Green Enantioselective Aldol Condensation Reaction.Experiment 41. Preparation of an Unsaturated Ketone via Michael and Aldol Condensation Reactions.Experiment 42. Preparation of Triphenylpyridine.Experiment 43. The Wittig Reaction: Preparation of 1,4-Diphenyl-1,3-Butadiene.Experiment 44. Relative Reactivities of Several Aromatic Compounds.Experiment 45. Nitration of Methyl Benzoate.Essay: Synthetic Dyes.Experiment 46. Preparation of Methyl Orange.Experiment 47. Preparation of Indigo.Experiment 48. Formulation of a Paint and Art Project.Essay: Local Anesthetics.Experiment 49. Benzocaine.Essay: Pheromones: Insect Attractants and Repellents.Experiment 50. N,N-Diethyl-m-toluamide: The Insect Repellent OFF".Essay: Sulfa Drugs.Experiment 51. Sulfa Drugs: Preparation of Sulfanilamide.Essay: Polymers and Plastics.Experiment 52. Preparation and Properties of Polymers: Polyester, Nylon, and Polystyrene.Essay: Diels-Alder Reactions and Insecticides.Experiment 53. The Diels-Alder Reaction of Cyclopentadiene with Maleic Anhydride.Experiment 54. The Diels-Alder Reaction with Anthracene-9-Methanol.Experiment 55. Photoreduction of Benzophenone and Rearrangement of Benzpinacol to Benzopinacolone.Essay: Fireflies and Photochemistry.Experiment 56. Luminol.Experiment 57. Identification of Unknowns.Experiment 58. Preparation of a C-4 or C-5 Acetate Ester.Experiment 59. Competing Nucleophiles in SN1 and SN2 Reactions: Investigations Using 2-Pentanol and 3-Pentanol.Experiment 60. Friedel-Crafts Acylation.Experiment 61. The Analysis of Antihistamine Drugs by Gas Chromatography-Mass Spectrometry.Experiment 62. The Use of Organozinc Reagents in Synthesis: An Exercise in Synthesis and Structure Proof by Spectroscopy.Experiment 63. Synthesis of Naproxen by Palladium Catalysis.Experiment 64. The Aldehyde Enigma.Experiment 65. Synthesis of Substituted Chalcones: A Guided-Inquiry Experience.Experiment 66. Green Epoxidation of Chalcones.Experiment 67. Cyclopropanation of Chalcones.Experiment 68. Michael and Aldol Condensation Reactions.Experiment 69. Esterification Reactions of Vanillin: The Use of NMR to Solve a Structure Proof Problem. Technique 1. Laboratory Safety.Technique 2. The Laboratory Notebook, Calculations, and Laboratory Records.Technique 3. Laboratory Glassware: Care and Cleaning.Technique 4. How to Find Data for Compounds: Handbooks and Catalogs.Technique 5. Measurement of Volume and Weight.Technique 6. Heating and Cooling Methods.Technique 7. Reaction Methods.Technique 8. Filtration.Technique 9. Physical Constants of Solids: The Melting Point.Technique 10. Solubility.Technique 11. Crystallization: Purification of Solids.Technique 12. Extractions, Separations, and Drying Agents.Technique 13. Physical Constants of Liquids: The Boiling Point and Density.Technique 14. Simple Distillation.Technique 15. Fractional Distillation, Azeotropes.Technique 16. Vacuum Distillation, Manometers.Technique 17. Sublimation.Technique 18. Steam Distillation.Technique 19. Column Chromatography.Technique 20. Thin-Layer Chromatography.Technique 21. High-Performance Liquid Chromatography (HPLC).Technique 22. Gas Chromatography.Technique 23. Polarimetry.Technique 24. Refractometry.Technique 25. Infrared Spectroscopy.Technique 26. Nuclear Magnetic Resonance Spectroscopy.Technique 27. Carbon-13 Nuclear Magnetic Resonance Spectroscopy.Technique 28. Mass Spectrometry.Technique 29. Guide to the Chemical Literature.Appendix 1: Tables of Unknowns and Derivatives.Appendix 2: Procedures for Preparing Derivatives.Appendix 3: Index of Spectra.Index."
in English
9781305968349
Organic chemistry
CHEMISTRY
Chemistry--Laboratory manuals
Chemistry--Organic--Laboratory manual
547.007 P28m 2018
A microscale approach to organic laboratory techniques / Donald L. Pavia, Gary M. Lampman, George S. Kriz, [and] Randall G. Engel. - Sixth edition - Boston, MA : Cengage Learning, 2018. - xvii, 1034 pages: illustrations 28 cm. - Cengage Learning Laboratory Series for Organic Chemistry .
Includes index
Experiment 1.Introduction to Microscale Laboratory.Experiment 2.Solubility.Experiment 3.Crystallization.Experiment 4.Extraction.Experiment 5.A Separation and Purification Scheme.Experiment 6.Chromatography.Experiment 7.Infrared Spectroscopy and Boiling Point Determination.Experiment 8.Simple and Fractional Distillation.Essay: Aspirin.Experiment 9.Acetylsalicylic Acid.Essay: Analgesics.Experiment 10. Isolation of the Active Ingredient in an Analgesic Drug.Experiment 11, Acetaminophen.Essay: Identification of Drugs.Experiment 12. TLC Analysis of Analgesic Drugs.Essay: Caffeine.Experiment 13. Isolation of Caffeine from Tea or Coffee.Essay: Esters -- Flavors and Fragrances.Experiment 14. Isopentyl Acetate (Banana Oil).Essay: Terpenes and Phenylpropanoids.Experiment 15. Essential Oils: Extraction of Oil of Cloves by Steam Distillation.Essay: Stereochemical Theory of Odor.Experiment 16. Spearmint and Caraway Oil: (+)- and (-)-Carvones.Essay: The Chemistry of Vision.Experiment 17. Isolation of Chlorophyll and Carotenoid Pigments from Spinach.Essay: Ethanol and Fermentation Chemistry.Experiment 18. Ethanol from Sucrose.Essay Molecular Modeling and Molecular Mechanics.Experiment 19. An Introduction to Molecular Modeling.Essay: Computational Chemistry -- Ab Initio and Semiempirical Methods.Experiment 20. Computational Chemistry.Experiment 21. Reactivities of Some Alkyl Halides.Experiment 22. Nucleophilic Substitution Reactions: Competing Nucleophiles.Experiment 23. Synthesis of n-Butyl Bromide and t-Pentyl Chloride.Experiment 24. 4-Methylcyclohexene.Essay: Fats and Oils.Experiment 25. Methyl Stearate from Methyl Oleate.Essay: Soap.Experiment 26. Preparation of Soap.Essay: Petroleum and Fossil Fuels.Experiment 27. Gas Chromatographic Analysis of Gasolines.Essay: Biofuels.Experiment 28. Biodiesel.Essay: Green Chemistry.Experiment 29. Chiral Reduction of Ethyl Acetoacetate; Optical Purity Determination.Experiment 30. Nitration of Aromatic Compounds Using a Recyclable Catalyst.Experiment 31. Reduction of Ketones Using Carrots as Biological Reducing Agents.Experiment 32. Resolution of Phenylethylamine and Determination of Optical Purity.Experiment 33. An Oxidation-Reduction Scheme: Borneol, Camphor, Isoborneol.Experiment 34. Multi-Step Reaction Sequences: The Conversion of Benzaldehydeto Benzilic Acid.Experiment 35. Triphenylmethanol and Benzoic Acid.Experiment 36. Aqueous-based Organozinc Reactions.Experiment 37. Sonogashira Coupling of Iodosubstituted Aromatic Compounds with Alkynes Using a Palladium Catalyst.Experiment 38. Grubbs-Catalyzed Metathesis of Eugenol with 1,4-Butanediol to Prepare a Natural Product.Experiment 39. The Aldol Condensation Reaction: Preparation of Benzalacetophenones (Chalcones).Experiment 40. A Green Enantioselective Aldol Condensation Reaction.Experiment 41. Preparation of an Unsaturated Ketone via Michael and Aldol Condensation Reactions.Experiment 42. Preparation of Triphenylpyridine.Experiment 43. The Wittig Reaction: Preparation of 1,4-Diphenyl-1,3-Butadiene.Experiment 44. Relative Reactivities of Several Aromatic Compounds.Experiment 45. Nitration of Methyl Benzoate.Essay: Synthetic Dyes.Experiment 46. Preparation of Methyl Orange.Experiment 47. Preparation of Indigo.Experiment 48. Formulation of a Paint and Art Project.Essay: Local Anesthetics.Experiment 49. Benzocaine.Essay: Pheromones: Insect Attractants and Repellents.Experiment 50. N,N-Diethyl-m-toluamide: The Insect Repellent OFF".Essay: Sulfa Drugs.Experiment 51. Sulfa Drugs: Preparation of Sulfanilamide.Essay: Polymers and Plastics.Experiment 52. Preparation and Properties of Polymers: Polyester, Nylon, and Polystyrene.Essay: Diels-Alder Reactions and Insecticides.Experiment 53. The Diels-Alder Reaction of Cyclopentadiene with Maleic Anhydride.Experiment 54. The Diels-Alder Reaction with Anthracene-9-Methanol.Experiment 55. Photoreduction of Benzophenone and Rearrangement of Benzpinacol to Benzopinacolone.Essay: Fireflies and Photochemistry.Experiment 56. Luminol.Experiment 57. Identification of Unknowns.Experiment 58. Preparation of a C-4 or C-5 Acetate Ester.Experiment 59. Competing Nucleophiles in SN1 and SN2 Reactions: Investigations Using 2-Pentanol and 3-Pentanol.Experiment 60. Friedel-Crafts Acylation.Experiment 61. The Analysis of Antihistamine Drugs by Gas Chromatography-Mass Spectrometry.Experiment 62. The Use of Organozinc Reagents in Synthesis: An Exercise in Synthesis and Structure Proof by Spectroscopy.Experiment 63. Synthesis of Naproxen by Palladium Catalysis.Experiment 64. The Aldehyde Enigma.Experiment 65. Synthesis of Substituted Chalcones: A Guided-Inquiry Experience.Experiment 66. Green Epoxidation of Chalcones.Experiment 67. Cyclopropanation of Chalcones.Experiment 68. Michael and Aldol Condensation Reactions.Experiment 69. Esterification Reactions of Vanillin: The Use of NMR to Solve a Structure Proof Problem. Technique 1. Laboratory Safety.Technique 2. The Laboratory Notebook, Calculations, and Laboratory Records.Technique 3. Laboratory Glassware: Care and Cleaning.Technique 4. How to Find Data for Compounds: Handbooks and Catalogs.Technique 5. Measurement of Volume and Weight.Technique 6. Heating and Cooling Methods.Technique 7. Reaction Methods.Technique 8. Filtration.Technique 9. Physical Constants of Solids: The Melting Point.Technique 10. Solubility.Technique 11. Crystallization: Purification of Solids.Technique 12. Extractions, Separations, and Drying Agents.Technique 13. Physical Constants of Liquids: The Boiling Point and Density.Technique 14. Simple Distillation.Technique 15. Fractional Distillation, Azeotropes.Technique 16. Vacuum Distillation, Manometers.Technique 17. Sublimation.Technique 18. Steam Distillation.Technique 19. Column Chromatography.Technique 20. Thin-Layer Chromatography.Technique 21. High-Performance Liquid Chromatography (HPLC).Technique 22. Gas Chromatography.Technique 23. Polarimetry.Technique 24. Refractometry.Technique 25. Infrared Spectroscopy.Technique 26. Nuclear Magnetic Resonance Spectroscopy.Technique 27. Carbon-13 Nuclear Magnetic Resonance Spectroscopy.Technique 28. Mass Spectrometry.Technique 29. Guide to the Chemical Literature.Appendix 1: Tables of Unknowns and Derivatives.Appendix 2: Procedures for Preparing Derivatives.Appendix 3: Index of Spectra.Index."
in English
9781305968349
Organic chemistry
CHEMISTRY
Chemistry--Laboratory manuals
Chemistry--Organic--Laboratory manual
547.007 P28m 2018